Vitamin D Receptor Antikörper (Internal Region)

Produktnummer ABIN6265989

Produktdetails anti-Vitamin D Receptor Antikörper

Target: Vitamin D Receptor (VDR)

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Vitamin D Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: Vitamin D Receptor Antibody detects endogenous levels of total Vitamin D Receptor.

Homologie: Pig,Horse,Chicken

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human Vitamin D Receptor, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu Vitamin D Receptor

Target: Vitamin D Receptor (VDR)

Andere Bezeichnung: VDR (VDR Produkte)

Synonyme: vdrbeta antikoerper, vdr0 antikoerper, LOC100136219 antikoerper, NR1I1-B antikoerper, gb:dq017633 antikoerper, vdr-b antikoerper, Ci-VDR-b antikoerper, VDR antikoerper, LOC100221284 antikoerper, vdr-A antikoerper, xVDR antikoerper, Nr1i1 antikoerper, vdr antikoerper, NR1I1 antikoerper, PPP1R163 antikoerper, vitamin D (1,25- dihydroxyvitamin D3) receptor antikoerper, vitamin D receptor antikoerper, vitamin D3 receptor A antikoerper, vitamin D receptor b antikoerper, nuclear receptor VDR-b antikoerper, vitamin D (1,25- dihydroxyvitamin D3) receptor L homeolog antikoerper, vitamin D (1,25-dihydroxyvitamin D3) receptor antikoerper, vitamin D receptor a antikoerper, vdr antikoerper, vdr0 antikoerper, VDR antikoerper, LOC100136219 antikoerper, vdrb antikoerper, vdr-b antikoerper, vdr.L antikoerper, Vdr antikoerper, vdra antikoerper

Substanzklasse: Chemical

Hintergrund:

Description: Nuclear receptor for calcitriol, the active form of vitamin D3 which mediates the action of this vitamin on cells. Enters the nucleus upon vitamin D3 binding where it forms heterodimers with the retinoid X receptor/RXR. The VDR-RXR heterodimers bind to specific response elements on DNA and activate the transcription of vitamin D3-responsive target genes. Recruited to promoters via its interaction with BAZ1B/WSTF which mediates the interaction with acetylated histones, an essential step for VDR-promoter association. Plays a central role in calcium homeostasis.

Gene: VDR

Molekulargewicht: 48kDa

Gen-ID: 7421

UniProt: P11473

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway