TIE1 Antikörper (pTyr1117)

Produktnummer ABIN8125505

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch TIE1 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für TIE1 Antikörper (pTyr1117) (ABIN8125505)

Target: TIE1 (tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TIE1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TIE1 Antikörper

Bindungsspezifität: pTyr1117

Verwendungszweck: TIE1 (Phospho Tyr1117) Antibody

Spezifität: This antibody detects endogenous levels of TIE1 (Phospho-Tyr1117) at Human, Mouse,Rat

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthesized peptide derived from human TIE1 (Phospho-Tyr1117)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu TIE1

Target: TIE1 (tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1))

Andere Bezeichnung: TIE1

Hintergrund:

Synonyms: Tyrosine-protein kinase receptor Tie-1 (EC 2.7.10.1)

Background: This gene encodes a member of the tyrosine protein kinase family. The encoded protein plays a critical role in angiogenesis and blood vessel stability by inhibiting angiopoietin 1 signaling through the endothelial receptor tyrosine kinase Tie2. Ectodomain cleavage of the encoded protein relieves inhibition of Tie2 and is mediated by multiple factors including vascular endothelial growth factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011],

Gene Name: TIE1 TIE

Protein Name: TIE1 (Phospho-Tyr1117)

Gen-ID: 7075

UniProt: P35590

Pathways: RTK Signalweg