TYK2 Antikörper (pTyr292)
Kurzübersicht für TYK2 Antikörper (pTyr292) (ABIN8125503)
Target
Alle TYK2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pTyr292
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Verwendungszweck
- Tyk 2 (Phospho Tyr292) Antibody
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Spezifität
- This antibody detects endogenous levels of Human Tyk 2 (Phospho Tyr292)
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Aufreinigung
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
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Immunogen
- Synthesized peptide derived from human Tyk 2 (Phospho Tyr292)
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Isotyp
- IgG
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Applikationshinweise
- WB 1:1000-2000 ELISA 1:5000-20000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C/1 year
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Haltbarkeit
- 12 months
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- TYK2 (Tyrosine Kinase 2 (TYK2))
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Andere Bezeichnung
- Tyk 2
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Hintergrund
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Synonyms: Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)
Background: tyrosine kinase 2(TYK2) Homo sapiens This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. [provided by RefSeq, Jul 2008],
Gene Name: TYK2
Protein Name: Tyk 2 (Phospho Tyr292)
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Gen-ID
- 7297
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UniProt
- P29597
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Pathways
- JAK-STAT Signalweg, Hepatitis C
Target
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