TYK2 Antikörper (pTyr1054)

Produktnummer ABIN8125502

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch TYK2 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für TYK2 Antikörper (pTyr1054) (ABIN8125502)

Target: TYK2 (Tyrosine Kinase 2 (TYK2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TYK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TYK2 Antikörper

Bindungsspezifität: pTyr1054

Verwendungszweck: Tyk2 (Phospho Tyr1054/1055) Antibody

Spezifität: This antibody detects endogenous levels of Human Tyk2 (phospho-Tyr1054 or 1055)

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthesized phosho peptide around human Tyk2 (Tyr1054 and 1055)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu TYK2

Target: TYK2 (Tyrosine Kinase 2 (TYK2))

Andere Bezeichnung: Tyk2

Hintergrund:

Synonyms: Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)

Background: tyrosine kinase 2(TYK2) Homo sapiens This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. [provided by RefSeq, Jul 2008],

Gene Name: TYK2

Protein Name: Tyk2 (Tyr1054/1055)

Gen-ID: 7297

UniProt: P29597

Pathways: JAK-STAT Signalweg, Hepatitis C