STING/TMEM173 Antikörper (pSer366)

Produktnummer ABIN8125357

Der Kaninchen Polyklonal anti-STING/TMEM173 Antikörper (ABIN8125357) detektiert spezifisch STING/TMEM173 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für STING/TMEM173 Antikörper (pSer366) (ABIN8125357)

Target: STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STING/TMEM173 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-STING/TMEM173 Antikörper

Bindungsspezifität: pSer366

Verwendungszweck: STING (Phospho Ser366) Antibody

Spezifität: This antibody detects endogenous levels of STING (Phospho-Ser366) at Human, Mouse,Rat

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthesized peptide derived from human STING (Phospho-Ser366)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu STING/TMEM173

Target: STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))

Andere Bezeichnung: STING

Hintergrund:

Synonyms: Transmembrane protein 173 (Endoplasmic reticulum interferon stimulator) (ERIS) (Mediator of IRF3 activation) (hMITA) (Stimulator of interferon genes protein) (hSTING)

Background: This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014],

Gene Name: TMEM173 ERIS MITA STING

Protein Name: STING (Phospho-Ser366)

Gen-ID: 340061

UniProt: Q86WV6

Pathways: Activation of Innate immune Response