SSRP1 Antikörper (AA 209-259)

Produktnummer ABIN8125000

Der Kaninchen Polyklonal anti-SSRP1 Antikörper (ABIN8125000) detektiert spezifisch SSRP1 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für SSRP1 Antikörper (AA 209-259) (ABIN8125000)

Target: SSRP1 (Structure Specific Recognition Protein 1 (SSRP1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SSRP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SSRP1 Antikörper

Bindungsspezifität: AA 209-259

Verwendungszweck: SSRP1 Antibody

Spezifität: This antibody detects endogenous levels of SSRP1 at Human/Mouse/Rat

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human SSRP1 AA range: 209-259

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu SSRP1

Target: SSRP1 (Structure Specific Recognition Protein 1 (SSRP1))

Andere Bezeichnung: SSRP1

Hintergrund:

Background: The protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63. An alternatively spliced transcript variant of this gene has been described, but its full-length nature is not known. [provided by RefSeq, Jul 2008],

Gene Name: SSRP1 FACT80

Protein Name: SSRP1

Gen-ID: 6749

UniProt: Q08945

Pathways: Chromatin Binding