SCP2 Antikörper (AA 338-388)

Produktnummer ABIN8124974

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch SCP2 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für SCP2 Antikörper (AA 338-388) (ABIN8124974)

Target: SCP2 (Sterol Carrier Protein 2 (SCP2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SCP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SCP2 Antikörper

Bindungsspezifität: AA 338-388

Verwendungszweck: NLTP Antibody

Spezifität: This antibody detects endogenous levels of NLTP at Human/Mouse/Rat

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human NLTP AA range: 338-388

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu SCP2

Target: SCP2 (Sterol Carrier Protein 2 (SCP2))

Andere Bezeichnung: NLTP

Hintergrund:

Background: This gene encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2), as a result of transcription initiation from 2 independently regulated promoters. The transcript initiated from the proximal promoter encodes the longer SCPx protein, and the transcript initiated from the distal promoter encodes the shorter SCP2 protein, with the 2 proteins sharing a common C-terminus. Evidence suggests that the SCPx protein is a peroxisome-associated thiolase that is involved in the oxidation of branched chain fatty acids, while the SCP2 protein is thought to be an intracellular lipid transfer protein. This gene is highly expressed in organs involved in lipid metabolism, and may play a role in Zellweger syndrome, in which cells are deficient in peroxisomes and have impaired bile acid synthesis. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms.[provided by RefSeq, Aug 2010],

Gene Name: SCP2

Protein Name: NLTP

Gen-ID: 6342

UniProt: P22307

Pathways: C21-Steroid Hormone Metabolic Process, Monocarboxylic Acid Catabolic Process