SYK Antikörper (pTyr352)
Kurzübersicht für SYK Antikörper (pTyr352) (ABIN8124902)
Target
Alle SYK Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pTyr352
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Verwendungszweck
- Syk (phospho Tyr352) Antibody
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Spezifität
- Phospho-Syk (Y352) Polyclonal Antibody detects endogenous levels of Syk protein only when phosphorylated at Y352.
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
- Synthesized phospho-peptide around the phosphorylation site of human Syk (phospho Tyr352)
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C/1 year
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Haltbarkeit
- 12 months
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- SYK (Spleen tyrosine Kinase (SYK))
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Andere Bezeichnung
- Syk
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Hintergrund
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Synonyms: SYK, Tyrosine-protein kinase SYK, Spleen tyrosine kinase, p72-Syk
Background: This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010],
Gene Name: SYK
Protein Name: Tyrosine-protein kinase SYK
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Gen-ID
- 6850
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UniProt
- P43405
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Pathways
- Fc-epsilon Rezeptor Signalübertragung, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Thromboxane A2 Receptor Signaling, BCR Signaling
Target
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