RPA1 Antikörper

Produktnummer ABIN8124316

Der Kaninchen Polyklonal anti-RPA1 Antikörper (ABIN8124316) detektiert spezifisch RPA1 in WB, ELISA und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte und Affe.

Kurzübersicht für RPA1 Antikörper (ABIN8124316)

Target: RPA1 (Replication Protein A1, 70kDa (RPA1))

Reaktivität: Human, Maus, Ratte, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RPA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-RPA1 Antikörper

Verwendungszweck: RFA1 Antibody

Spezifität: This antibody detects endogenous levels of Human,Monkey,Mouse,Rat RFA1

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human RFA1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu RPA1

Target: RPA1 (Replication Protein A1, 70kDa (RPA1))

Andere Bezeichnung: RFA1

Hintergrund:

Synonyms: Replication protein A 70 kDa DNA-binding subunit (RP-A p70, Replication factor A protein 1, RF-A protein 1, Single-stranded DNA-binding protein)

Background: function:It participates in a very early step in initiation. RP-A is a single-stranded DNA-binding protein. Absolutely required for simian virus 40 DNA replication in vitro.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the replication factor A protein 1 family.,subunit:Heterotrimer of 70, 32 and 14 kDa chains. The DNA-binding activity may reside exclusively on the 70 kDa subunit. Interacts with RIP and XPA. Interacts with RPA4.,

Gene Name: RPA1 REPA1 RPA70

Protein Name: RFA1

Gen-ID: 6117

UniProt: P27694

Pathways: Telomere Maintenance, DNA Reparatur, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA