rala Antikörper (AA 170-250)

Produktnummer ABIN8124256

Der Kaninchen Polyklonal anti-rala Antikörper (ABIN8124256) detektiert spezifisch rala in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für rala Antikörper (AA 170-250) (ABIN8124256)

Target: rala (Ras-related Protein Ral-A (rala))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser rala Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-rala Antikörper

Bindungsspezifität: AA 170-250

Verwendungszweck: RASL1 Antibody

Spezifität: RASL1 Polyclonal Antibody detects endogenous levels of protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human protein . at AA range: 170-250

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000 ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu rala

Target: rala (Ras-related Protein Ral-A (rala))

Andere Bezeichnung: RASL1

Hintergrund:

Background: The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. These proteins stimulate the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member contains domains which are characteristic of the GAP1 subfamily of RasGAP proteins but, in contrast to the other GAP1 family members, this protein is strongly and selectively expressed in endocrine tissues. Alternatively spliced transcript variants that encode different isoforms have been described [provided by RefSeq, Jul 2010],

Gene Name: RASAL1 RASAL

Protein Name: RasGAP-activating-like protein 1

Gen-ID: 8437

UniProt: O95294

Pathways: Neurotrophin Signalübertragung, SARS-CoV-2 Protein Interaktom