rala Antikörper (AA 1-203)

Produktnummer ABIN7167390

Produktdetails anti-rala Antikörper

Target: rala (Ras-related Protein Ral-A (rala))

Bindungsspezifität: AA 1-203

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser rala Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Ras-related protein Ral-A protein (1-203AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200, IF:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu rala

Target: rala (Ras-related Protein Ral-A (rala))

Andere Bezeichnung: RALA (rala Produkte)

Synonyme: 3010001O15Rik antikoerper, AW322615 antikoerper, Ral antikoerper, Rasl1 antikoerper, RAL antikoerper, v-ral simian leukemia viral oncogene A (ras related) antikoerper, RAS like proto-oncogene A antikoerper, Rala antikoerper, RALA antikoerper

Hintergrund:

Background: Multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Accomplishes its multiple functions by interacting with distinct downstream effectors. Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles. Plays a role in the early stages of cytokinesis and is required to tether the exocyst to the cytokinetic furrow. The RALA-exocyst complex regulates integrin-dependent membrane raft exocytosis and growth signaling. Key regulator of LPAR1 signaling and competes with GRK2 for binding to LPAR1 thus affecting the signaling properties of the receptor. Required for anchorage-independent proliferation of transformed cells.

Aliases: MGC48949 antibody, Ral a antibody, Ral A protein antibody, RAL antibody, RALA antibody, RALA_HUMAN antibody, Ras family small GTP binding protein RALA antibody, RAS like protein A antibody, Ras related protein RalA antibody, Ras-related protein Ral-A antibody, v ral simian leukemia viral oncogene homolog A (ras related) antibody, v ral simian leukemia viral oncogene homolog A antibody

UniProt: P11233

Pathways: Neurotrophin Signalübertragung, SARS-CoV-2 Protein Interaktom