PKC Antikörper (AA 450-550)

Produktnummer ABIN8124064

Der Maus Monoklonal anti-PKC Antikörper (Klon AB2366) (ABIN8124064) detektiert spezifisch PKC in WB, IF und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Rind (Kuh) und Kaninchen.

Kurzübersicht für PKC Antikörper (AA 450-550) (ABIN8124064)

Target: PKC (Protein Kinase C (PKC))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Kaninchen

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PKC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), ELISA

Klon: AB2366

Produktdetails anti-PKC Antikörper

Bindungsspezifität: AA 450-550

Verwendungszweck: PKC mouse mAb

Spezifität: This antibody detects endogenous levels of PKC protein.

Aufreinigung: The antibody was purified by protein G affinity chromatography.

Immunogen: A synthetic peptide corresponding to the amino acid region 450 - 550 of the human PKC protein.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at-20°C. Avoid freeze / thaw cycles.

Details zu PKC

Target: PKC (Protein Kinase C (PKC))

Andere Bezeichnung: PKC

Hintergrund:

Synonyms: Protein kinase C alpha type, PKC-A, PKC-alpha, PRKCA, PKCA, PRKACA, Protein kinase C beta type, PKC-B, PKC-beta, PRKCB, PKCB, PRKCB1, Protein kinase C gamma type, PKC-gamma, PRKCG, PKCG

Background: protein kinase C alpha (PRKCA) Homo sapiens Protein kinase C (PKC) is a family of serine-and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca (2+) handling in myocytes. [provided by RefSeq, Jul 2

Gene Name: PRKCA PRKCB PRKCG

Protein Name: PKC

Gen-ID: 5578

UniProt: P17252

Pathways: T-Zell Rezeptor Signalweg, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Phototransduction