PKC Antikörper (C-Term)

Produktnummer ABIN7860719

Dieser Maus Monoklonal Antikörper detektiert spezifisch PKC in WB und IHC. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für PKC Antikörper (C-Term) (ABIN7860719)

Target: PKC (Protein Kinase C (PKC))

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PKC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Klon: 133

Produktdetails anti-PKC Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: Protein Kinase C α / PRKCA Antibody

Spezifität: Protein Kinase C alpha (PKC°™) is involved in the regulation of cell proliferation during cell cycle progression. This is a calcium-activated, phospholipid-dependent, serine- and threonine-specific enzyme. May play a role in cell motility by phosphorylating CSPG4. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. Clone 133 recognizes the °™ isoform of PKC°™ and binds to a sequence at the C terminus of PKC°™ to detect its expression in vitro.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Full-length protein corresponding to PKC alpha. Recognizes sequence PQFVHPILQSAV at the C terminus at PKCα.

Isotyp: IgG2a, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu PKC

Target: PKC (Protein Kinase C (PKC))

Andere Bezeichnung: Protein Kinase C α

Hintergrund:

PKC alpha, PKC-A, PKC-alpha, PKCA, PRKCA, Protein kinase C alpha, Protein kinase C alpha type

Normal human kidney or tonsil tissue. HEK293 whole cell lysates.

Molekulargewicht: 77kDa

Gen-ID: 5578, 531704, 708867

UniProt: P17252

Pathways: T-Zell Rezeptor Signalweg, Regulation of G-Protein Coupled Receptor Protein Signaling, Interaction of EGFR with phospholipase C-gamma, Phototransduction