PRSS2 Antikörper

Produktnummer ABIN8124020

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch PRSS2 in WB, IHC und IF. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für PRSS2 Antikörper (ABIN8124020)

Target: PRSS2 (Protease, serine, 2 (Trypsin 2) (PRSS2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRSS2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-PRSS2 Antikörper

Verwendungszweck: TRY2 Antibody

Spezifität: This antibody detects endogenous levels of human TRY2

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human TRY2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:50-200, WB 1:500-2000. IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu PRSS2

Target: PRSS2 (Protease, serine, 2 (Trypsin 2) (PRSS2))

Andere Bezeichnung: TRY2

Hintergrund:

Synonyms: Trypsin-2 (EC 3.4.21.4, Anionic trypsinogen, Serine protease 2, Trypsin II)

Background: This gene belongs to the trypsin family of serine proteases and encodes anionic trypsinogen. It is part of a cluster of trypsinogen genes that are located within the T cell receptor beta locus. Enzymes of this family cleave peptide bonds that follow lysine or arginine residues. This protein is found at high levels in pancreatic juice and its upregulation is a characteristic feature of pancreatitis. This protein has also been found to activate pro-urokinase in ovarian tumors, suggesting a function in tumor invasion. In addition, this enzyme is able to cleave across the type II collagen triple helix in rheumatoid arthritis synovitis tissue, potentially participating in the degradation of type II collagen-rich cartilage matrix. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jan 2015],

Gene Name: PRSS2 TRY2 TRYP2

Protein Name: TRY2

Gen-ID: 5645

UniProt: P07478