PTRF Antikörper (pTyr156)

Produktnummer ABIN8123877

Der Kaninchen Polyklonal anti-PTRF Antikörper wird verwendet zum Nachweis von PTRF in Proben von Human, Maus und Ratte. Er wurde validiert für WB.

Kurzübersicht für PTRF Antikörper (pTyr156) (ABIN8123877)

Target: PTRF (Polymerase I and Transcript Release Factor (PTRF))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PTRF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PTRF Antikörper

Bindungsspezifität: pTyr156

Verwendungszweck: PTRF (Phospho Tyr156) Antibody

Spezifität: This antibody detects endogenous levels of PTRF (Phospho-Tyr156) at Human, Mouse,Rat

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthesized peptide derived from human PTRF (Phospho-Tyr156)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu PTRF

Target: PTRF (Polymerase I and Transcript Release Factor (PTRF))

Andere Bezeichnung: PTRF

Hintergrund:

Synonyms: Polymerase I and transcript release factor (Cavin-1)

Background: This gene encodes a protein that enables the dissociation of paused ternary polymerase I transcription complexes from the 3' end of pre-rRNA transcripts. This protein regulates rRNA transcription by promoting the dissociation of transcription complexes and the reinitiation of polymerase I on nascent rRNA transcripts. This protein also localizes to caveolae at the plasma membrane and is thought to play a critical role in the formation of caveolae and the stabilization of caveolins. This protein translocates from caveolae to the cytoplasm after insulin stimulation. Caveolae contain truncated forms of this protein and may be the site of phosphorylation-dependent proteolysis. This protein is also thought to modify lipid metabolism and insulin-regulated gene expression. Mutations in this gene result in a disorder characterized by generalized lipodystrophy and muscular dystrop

Gene Name: PTRF FKSG13

Protein Name: PTRF (Phospho-Tyr156)

Gen-ID: 284119

UniProt: Q6NZI2