Podoplanin Antikörper (AA 23-100)
Kurzübersicht für Podoplanin Antikörper (AA 23-100) (ABIN8123829)
Target
Alle Podoplanin (PDPN) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 23-100
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Verwendungszweck
- Podoplanin mouse mAb
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Spezifität
- The antibody can specifically recognize human Podoplanin protein.
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Aufreinigung
- The antibody was purified by affinity chromatography using a specific immunogen.
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Immunogen
- A synthetic peptide corresponding to the amino acid region 23 - 100 of the human Podoplanin protein.
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Isotyp
- IgG
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Applikationshinweise
- IHC, 1:50-1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid freeze / thaw cycles
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at-20°C. Avoid freeze / thaw cycles.
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- Podoplanin (PDPN)
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Andere Bezeichnung
- Podoplanin
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Hintergrund
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Synonyms: Aggrus, Glycoprotein 36, Gp36, PA2. 26 antigen, T1-alpha, T1A
Background: Podoplanin, also known as D2-40 or M2A, is a 38 kDa type I transmembrane mucin with multiple O-glycosylation sites. It is highly expressed in lymphatic endothelial cells, but not in blood vessels. In addition, it is also expressed in a variety of cells, such as mesothelial cells and type I alveolar epithelial cells, follicular dendritic cells, reticular cells, ovarian and testicular germ cells. Podoplanin is a very useful marker to distinguish malignant mesothelioma and adenocarcinoma, seminoma and follicular dendritic cell sarcoma. It is also the main choice to show and quantify lymphatic and intravascular tumor infiltration.
Gene Name: PDPN
Protein Name: Podoplanin
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Gen-ID
- 10630
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UniProt
- Q86YL7
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Pathways
- Dicarboxylic Acid Transport
Target
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