NKX3-1 Antikörper (AA 1-100)

Produktnummer ABIN8123352

Der Maus Monoklonal anti-NKX3-1 Antikörper wird verwendet zum Nachweis von NKX3-1 in Proben von Human. Er wurde validiert für IHC, WB, ELISA und IF.

Kurzübersicht für NKX3-1 Antikörper (AA 1-100) (ABIN8123352)

Target: NKX3-1 (NK3 Homeobox 1 (NKX3-1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser NKX3-1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Western Blotting (WB), ELISA, Immunofluorescence (IF)

Klon: AB1400

Produktdetails anti-NKX3-1 Antikörper

Bindungsspezifität: AA 1-100

Verwendungszweck: NKX3.1 mouse mAb

Spezifität: The antibody can specifically recognize human NKX3. 1 protein.

Aufreinigung: The antibody was purified by protein G affinity chromatography.

Immunogen: A synthetic peptide corresponding to the amino acid region 1 - 100 of the human NKX3. 1 protein.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC, 1:200-1:1000 | WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at-20°C. Avoid freeze / thaw cycles.

Details zu NKX3-1

Target: NKX3-1 (NK3 Homeobox 1 (NKX3-1))

Andere Bezeichnung: NKX3.1

Hintergrund:

Synonyms: BAPX 2, BAPX2, Homeobox protein NK-3 homolog A, Homeobox protein Nkx 3. 1, Homeobox protein Nkx-3. 1, Homeobox protein Nkx3. 1, NK homeobox (Drosophila) family 3 A, NK homeobox family 3 A, NK homeobox, family 3, member A, NK3 homeobox 1, NK3 transcription factor homolog A, NK3 transcription factor related locus 1, NKX 3, Nkx 3. 1, NKX 3A, NKX3 1, NKX3, Nkx3-1, NKX3. 1, Nkx3. 1, Mouse, homolog of, NKX31_HUMAN, NKX3A

Background: NKX3. 1 is a nuclear transcription factor and a negative regulator of the growth of prostatic epithelial cells. Its mRNA transcription level is regulated by androgens and plays an important role in the occurrence and differentiation of prostate organs and the maintenance of the function of mature organs. NKX3. 1 has high sensitivity and specificity in benign prostatic hyperplasia and prostate cancer, and can be used as one of the specific markers to distinguish prostate cancer, benign prostatic hyperplasia and non prostate cancer. It is also expressed in mucous glands of testis, ureter and pulmonary bronchus.

Gene Name: NKX3-1

Protein Name: NKX3. 1

Gen-ID: 4824

UniProt: Q99801

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Positive Regulation of Endopeptidase Activity, Positive Regulation of Response to DNA Damage Stimulus