NBR1 Antikörper

Produktnummer ABIN8123261

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch NBR1 in IHC und IF. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für NBR1 Antikörper (ABIN8123261)

Target: NBR1 (Neighbor of BRCA1 Gene 1 (NBR1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NBR1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-NBR1 Antikörper

Verwendungszweck: NBR1 Antibody

Spezifität: The antibody detects endogenous NBR1 protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Recombinant Protein of NBR1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:50-300. IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu NBR1

Target: NBR1 (Neighbor of BRCA1 Gene 1 (NBR1))

Andere Bezeichnung: NBR1

Hintergrund:

Synonyms: Next to BRCA1 gene 1 protein (Cell migration-inducing gene 19 protein, Membrane component chromosome 17 surface marker 2, Neighbor of BRCA1 gene 1 protein, Protein 1A1-3B)

Background: The protein encoded by this gene was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled-coil motif, which is present in many genes with transformation potential. It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. This gene is located on a region of chromosome 17q21.1 that is in close proximity to the BRCA1 tumor suppressor gene. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2014],

Gene Name: NBR1 1A13B KIAA0049 M17S2 MIG19

Protein Name: Next to BRCA1 gene 1 protein (Cell migration-inducing gene 19 protein) (Membrane component chromosome 17 surface marker 2) (Neighbor of BRCA1 gene 1 protein) (Protein 1A1-3B)

Gen-ID: 4077

UniProt: Q14596

Pathways: Autophagie