NTAN1 Antikörper (AA 83-133)
Kurzübersicht für NTAN1 Antikörper (AA 83-133) (ABIN8123212)
Target
Alle NTAN1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 83-133
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Verwendungszweck
- NTAN1 Antibody
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Spezifität
- This antibody detects endogenous levels of NTAN1 at Human/Mouse
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
- Synthesized peptide derived from human NTAN1 AA range: 83-133
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500-2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C/1 year
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Haltbarkeit
- 12 months
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- NTAN1 (N-terminal Asparagine Amidase (NTAN1))
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Andere Bezeichnung
- NTAN1
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Hintergrund
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Background: The protein encoded by this gene functions in a step-wise process of protein degradation through the N-end rule pathway. This protein acts as a tertiary destabilizing enzyme that deamidates N-terminal L-Asn residues on proteins to produce N-terminal L-Asp. L-Asp substrates are subsequently conjugated to L-Arg, which is recognized by specific E3 ubiquitin ligases and targeted to the proteasome. Pseudogenes of this gene are located on the long arms of chromosomes 8, 10 and 12. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jul 2012],
Gene Name: NTAN1
Protein Name: NTAN1
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Gen-ID
- 123803
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UniProt
- Q96AB6
Target
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