NTAN1 Antikörper (AA 1-310)

Produktnummer ABIN7268787

Produktdetails anti-NTAN1 Antikörper

Target: NTAN1 (N-terminal Asparagine Amidase (NTAN1))

Bindungsspezifität: AA 1-310

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NTAN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: NTAN1 Rabbit pAb

Sequenz: MPLLVEGRRV RLPQSAGDLV RAHPPLEERA RLLRGQSVQQ VGPQGLLYVQ QRELAVTSPK DGSISILGSD DATTCHIVVL RHTGNGATCL THCDGTDTKA EVPLIMNSIK SFSDHAQCGR LEVHLVGGFS DDRQLSQKLT HQLLSEFDRQ EDDIHLVTLC VTELNDREEN ENHFPVIYGI AVNIKTAEIY RASFQDRGPE EQLRAARTLA GGPMISIYDA ETEQLRIGPY SWTPFPHVDF WLHQDDKQIL ENLSTSPLAE PPHFVEHIRS TLMFLKKHPS PAHTLFSGNK ALLYKKNEDG LWEKISSPGS

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-310 of human NTAN1 (NP_775745.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:200 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu NTAN1

Target: NTAN1 (N-terminal Asparagine Amidase (NTAN1))

Andere Bezeichnung: NTAN1 (NTAN1 Produkte)

Synonyme: PNAA antikoerper, PNAD antikoerper, N-terminal Asn amidase antikoerper, N-terminal asparagine amidase antikoerper, Ntan1 antikoerper, NTAN1 antikoerper

Hintergrund: The protein encoded by this gene functions in a step-wise process of protein degradation through the N-end rule pathway. This protein acts as a tertiary destabilizing enzyme that deamidates N-terminal L-Asn residues on proteins to produce N-terminal L-Asp. L-Asp substrates are subsequently conjugated to L-Arg, which is recognized by specific E3 ubiquitin ligases and targeted to the proteasome. Pseudogenes of this gene are located on the long arms of chromosomes 8, 10 and 12. Alternative splicing results in multiple transcript variants that encode different protein isoforms.,NTAN1,PNAA,PNAD,Cell Biology & Developmental Biology,Ubiquitin,NTAN1

Molekulargewicht: 34kDa

Gen-ID: 123803

UniProt: Q96AB6