MMP7 Antikörper (Cleaved-Tyr95)

Produktnummer ABIN8122803

Der Kaninchen Polyklonal anti-MMP7 Antikörper wird verwendet zum Nachweis von MMP7 in Proben von Human, Ratte und Maus. Er wurde validiert für WB, IHC und ELISA.

Kurzübersicht für MMP7 Antikörper (Cleaved-Tyr95) (ABIN8122803)

Target: MMP7 (Matrix Metallopeptidase 7 (Matrilysin, Uterine) (MMP7))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MMP7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-MMP7 Antikörper

Bindungsspezifität: Cleaved-Tyr95

Verwendungszweck: MMP7 (Cleaved-Tyr95) Antibody

Spezifität: This antibody detects endogenous levels of Human,Mouse,Rat MMP7 (Cleaved-Tyr95, protein was cleaved amino acid sequence between 94-95 )

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthesized peptide derived from human MMP7 (Cleaved-Tyr95)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu MMP7

Target: MMP7 (Matrix Metallopeptidase 7 (Matrilysin, Uterine) (MMP7))

Andere Bezeichnung: MMP7

Hintergrund:

Synonyms: Matrilysin (EC 3.4.24.23, Matrin, Matrix metalloproteinase-7, MMP-7, Pump-1 protease, Uterine metalloproteinase)

Background: catalytic activity:Cleavage of 14-Ala-|-Leu-15 and 16-Tyr-|-Leu-17 in B chain of insulin. No action on collagen types I, II, IV, V. Cleaves gelatin chain alpha-2(I) > alpha-1(I).,cofactor:Binds 2 calcium ions per subunit.,cofactor:Binds 2 zinc ions per subunit.,domain:The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.,function:Degrades casein, gelatins of types I, III, IV, and V, and fibronectin. Activates procollagenase.,similarity:Belongs to the peptidase M10A family.,

Gene Name: MMP7 MPSL1 PUMP1

Protein Name: MMP7 (Cleaved-Tyr95)

Gen-ID: 4316

UniProt: P09237

Pathways: Production of Molecular Mediator of Immune Response