LTB Antikörper (AA 41-90)

Produktnummer ABIN8122711

Der Kaninchen Polyklonal anti-LTB Antikörper (ABIN8122711) detektiert spezifisch LTB in WB, ELISA, IHC und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für LTB Antikörper (AA 41-90) (ABIN8122711)

Target: LTB (Lymphotoxin beta (TNF Superfamily, Member 3) (LTB))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LTB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-LTB Antikörper

Bindungsspezifität: AA 41-90

Verwendungszweck: LT-β Antibody

Spezifität: The antibody detects endogenous LT-β

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthetic peptide from human protein at AA range: 41-90

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:50-200, ELISA 1:10000-20000,WB 1:500-2000. IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu LTB

Target: LTB (Lymphotoxin beta (TNF Superfamily, Member 3) (LTB))

Andere Bezeichnung: LT-beta

Hintergrund:

Synonyms: Lymphotoxin-beta (LT-beta, Tumor necrosis factor C, TNF-C, Tumor necrosis factor ligand superfamily member 3)

Background: Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex (e.g. 1 Molecule alpha/2 Molecules beta) and this complex is the primary ligand for the lymphotoxin-beta receptor. The minor complex is lymphotoxin-alpha 2/beta 1. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is unable to complex with lymphotoxin-alpha suggesting a function for lymphotoxin-beta which is independent of lympyhotoxin-alpha. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],

Gene Name: LTB TNFC TNFSF3

Protein Name: Lymphotoxin-beta (LT-beta) (Tumor necrosis factor C) (TNF-C) (Tumor necrosis factor ligand superfamily member 3)

Gen-ID: 4050

UniProt: Q06643

Pathways: NF-kappaB Signalweg