KPNA6 Antikörper (AA 404-454)

Produktnummer ABIN8122417

Der Kaninchen Polyklonal anti-KPNA6 Antikörper (ABIN8122417) detektiert spezifisch KPNA6 in WB und IP. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für KPNA6 Antikörper (AA 404-454) (ABIN8122417)

Target: KPNA6 (Karyopherin alpha 6 (Importin alpha 7) (KPNA6))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KPNA6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Produktdetails anti-KPNA6 Antikörper

Bindungsspezifität: AA 404-454

Verwendungszweck: KPNA6 Antibody

Spezifität: This antibody detects endogenous levels of KPNA6 at Human/Mouse

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human KPNA6 AA range: 404-454

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu KPNA6

Target: KPNA6 (Karyopherin alpha 6 (Importin alpha 7) (KPNA6))

Andere Bezeichnung: KPNA6

Hintergrund:

Synonyms: Importin subunit alpha-7 (Karyopherin subunit alpha-6)

Background: Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore.The protein encoded byThis gene is a member of the importin alpha family. [provided by RefSeq, Jul 2008],

Gene Name: KPNA6 IPOA7

Protein Name: KPNA6

Gen-ID: 23633

UniProt: O60684

Pathways: Protein targeting to Nucleus