IBTK Antikörper (AA 410-490)
Kurzübersicht für IBTK Antikörper (AA 410-490) (ABIN8122183)
Target
Alle IBTK Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 410-490
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Verwendungszweck
- IBTK Antibody
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Spezifität
- IBTK Polyclonal Antibody detects endogenous levels of protein.
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
- Synthesized peptide derived from human protein . at AA range: 410-490
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500-2000 ELISA 1:5000-20000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C/1 year
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Haltbarkeit
- 12 months
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- IBTK (Inhibitor of Bruton Agammaglobulinemia Tyrosine Kinase (IBTK))
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Andere Bezeichnung
- IBTK
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Hintergrund
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Background: Bruton tyrosine kinase (BTK) is a protein tyrosine kinase that is expressed in B cells, macrophages, and neutrophils.The protein encoded by this gene binds to BTK and downregulates BTK's kinase activity. In addition, the encoded protein disrupts BTK-mediated calcium mobilization and negatively regulates the activation of nuclear factor-kappa-B-driven transcription. This gene has a pseudogene on chromosome 18. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014],
Gene Name: IBTK BTKI KIAA1417
Protein Name: Inhibitor of Bruton tyrosine kinase (IBtk)
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Gen-ID
- 25998
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UniProt
- Q9P2D0
Target
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