HNF1A Antikörper (pSer247)
Kurzübersicht für HNF1A Antikörper (pSer247) (ABIN8122096)
Target
Alle HNF1A Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pSer247
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Verwendungszweck
- HNF1α (Phospho Ser247) Antibody
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Spezifität
- This antibody detects endogenous levels of Human HNF1α (phospho-Ser247)
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Aufreinigung
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
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Immunogen
- Synthesized phosho peptide around human HNF1alpha (Ser247)
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Isotyp
- IgG
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Applikationshinweise
- WB 1:1000-2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C/1 year
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Haltbarkeit
- 12 months
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- HNF1A (HNF1 Homeobox A (HNF1A))
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Andere Bezeichnung
- HNF1alpha
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Hintergrund
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Synonyms: Hepatocyte nuclear factor 1-alpha (HNF-1-alpha) (HNF-1A) (Liver-specific transcription factor LF-B1) (LFB1) (Transcription factor 1) (TCF-1)
Background: The protein encoded by this gene is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015],
Gene Name: HNF1A TCF1
Protein Name: HNF1α (Ser247)
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Gen-ID
- 6927
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UniProt
- P20823
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Pathways
- Hormone Transport, Carbohydrate Homeostasis
Target
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