HNF1A Antikörper (AA 431-631)

Produktnummer ABIN3042451

Produktdetails anti-HNF1A Antikörper

Target: HNF1A (HNF1 Homeobox A (HNF1A))

Bindungsspezifität: AA 431-631

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HNF1A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit IgG polyclonal antibody for Hepatocyte nuclear factor 1-alpha(HNF1A) detection. Tested with WB in Human,Rat.

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Hepatocyte nuclear factor 1-alpha(HNF1A) detection. Tested with WB in Human,Rat.
Gene Name: HNF1 homeobox A
Protein Name: Hepatocyte nuclear factor 1-alpha

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human HNF1 recombinant protein (Position: A431-Q631). Human HNF1 shares 93% and 92% amino acid (aa) sequences identity with mouse and rat HNF1, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, The detection limit for HNF1 is approximately 0.25 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Referenzen für anti-HNF1A Antikörper (ABIN3042451)

Dai, Cai, Wu, Chen, Han: "Protocatechuic acid inhibits hepatitis B virus replication by activating ERK1/2 pathway and down-regulating HNF4α and HNF1α in vitro." in: Life sciences, Vol. 180, pp. 68-74, (2017) (PubMed).

Details zu HNF1A

Target: HNF1A (HNF1 Homeobox A (HNF1A))

Andere Bezeichnung: HNF1A (HNF1A Produkte)

Synonyme: HNF-1A antikoerper, HNF1 antikoerper, IDDM20 antikoerper, LFB1 antikoerper, MODY3 antikoerper, TCF-1 antikoerper, TCF1 antikoerper, HNF-1a antikoerper, AI323641 antikoerper, HNF1-alpha antikoerper, HNF1[a] antikoerper, Hnf-1 antikoerper, Hnf1alpha antikoerper, Tcf-1 antikoerper, Tcf1 antikoerper, HNF-1-alpha antikoerper, HNF-1alpha antikoerper, LF-B1 antikoerper, Lfb1 antikoerper, HNF-1 antikoerper, HNF1A antikoerper, tcf1 antikoerper, FB1b antikoerper, HNF1b antikoerper, XLFB1b1 antikoerper, hnf1-B antikoerper, lfb1b antikoerper, mody3 antikoerper, tcf1-B antikoerper, tcfb-A antikoerper, HNF-1-alpha-A antikoerper, HNF-1A-A antikoerper, LFB1a1 antikoerper, TCF-1-A antikoerper, XLFB1 antikoerper, XLFB1b antikoerper, hnf1-a antikoerper, hnf1a antikoerper, hnf1a-a antikoerper, hnf1a-b antikoerper, hnf1a.L antikoerper, tcf1-A antikoerper, xx:af244934-22s antikoerper, HNF1 homeobox A antikoerper, HNF1 homeobox A L homeolog antikoerper, HNF1 homeobox A S homeolog antikoerper, HNF1 homeobox a antikoerper, HNF1A antikoerper, Hnf1a antikoerper, hnf1a antikoerper, hnf1a.L antikoerper, hnf1a.S antikoerper

Hintergrund: HNF1 homeobox A (hepatocyte nuclear factor 1 homeobox A), also known as HNF1A or TCF1, is a human gene. It is mapped to chromosome 12q24.3. The protein encoded by this gene is a transcription factor that is highly expressed in the liver and is involved in the regulation of the expression of several liver-specific genes. HNF1A can function as a dimer. What's more, deletion of the HNF1A activation domains or interruption of the HNF1-binding sites in the LCT promoter resulted in complete loss of transcriptional activity.

Synonyms: Albumin proximal factor antibody|Hepatic nuclear factor 1 alpha antibody|Hepatic nuclear factor 1 antibody|Hepatic transcription factor 1 alpha antibody|Hepatic transcription factor 1 antibody|Hepatocyte nuclear factor 1-alpha antibody|HNF 1 antibody|HNF 1A antibody|HNF-1-alpha antibody|HNF-1A antibody|HNF1A antibody|HNF1A_HUMAN antibody|Interferon production regulator factor antibody|LF B1 antibody|LF B1 hepatic nuclear factor antibody|LFB 1 antibody|LFB1 antibody|LFB1 hepatic nuclear factor antibody|Liver specific transcription factor LF B1 antibody|Liver specific transcription factor LFB1 antibody|Liver-specific transcription factor LF-B1 antibody|Maturity onset diabetes of the young 3 antibody|MODY 3 antibody|MODY3 antibody|TCF 1 antibody|TCF-1 antibody|TCF1 antibody|Transcription factor 1 antibody|Transcription factor 1 hepatic antibody

Gen-ID: 6927

UniProt: P20823

Pathways: Hormone Transport, Carbohydrate Homeostasis