HSPB8 Antikörper

Produktnummer ABIN8121889

Der Kaninchen Polyklonal anti-HSPB8 Antikörper (ABIN8121889) detektiert spezifisch HSPB8 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für HSPB8 Antikörper (ABIN8121889)

Target: HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HSPB8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-HSPB8 Antikörper

Verwendungszweck: Crystallin-αC Antibody

Spezifität: The antibody detects endogenous Crystallin-αC protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Recombinant Protein of Crystallin-alphaC

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4, containing 0.5 % BSA, 0.02 % sodium azide as Preservative and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu HSPB8

Target: HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))

Andere Bezeichnung: Crystallin-alphaC

Hintergrund:

Synonyms: HSPB8, CRYAC, E2IG1, HSP22, PP1629, Heat shock protein beta-8, HspB8, Alpha-crystallin C chain, E2-induced gene 1 protein, Protein kinase H11, Small stress protein-like protein HSP22

Background: The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. [provided by RefSeq, Jul 2008],

Gene Name: HSPB8

Protein Name: Heat shock protein beta-8

Gen-ID: 26353

UniProt: Q9UJY1