Fascin Antikörper

Produktnummer ABIN8121394

Der Kaninchen Monoklonal anti-Fascin Antikörper (Klon AB1621) (ABIN8121394) detektiert spezifisch Fascin in WB, IHC, IF, ELISA und IP. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte und Maus.

Kurzübersicht für Fascin Antikörper (ABIN8121394)

Target: Fascin (FSCN1)

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Fascin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA, Immunoprecipitation (IP)

Klon: AB1621

Produktdetails anti-Fascin Antikörper

Verwendungszweck: Fascin Rabbit mAb

Spezifität: This antibody detects endogenous levels of Fascin (55 kDa actin-bundling protein) (Singed-like protein) (p55) protein.

Aufreinigung: The antibody was purified by protein A affinity chromatography.

Immunogen: Recombinant protein (or fragment).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB, 1:10000-1:20000 | IHC, 1:1000-1:5000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at-20°C. Avoid freeze / thaw cycles.

Details zu Fascin

Target: Fascin (FSCN1)

Andere Bezeichnung: Fascin

Hintergrund:

Synonyms: Fascin (55 kDa actin-bundling protein) (Singed-like protein) (p55)

Background: This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15. [provided by RefSeq, Sep 2011]

Gene Name: FSCN1 FAN1 HSN SNL

Protein Name: Fascin (55 kDa actin-bundling protein) (Singed-like protein) (p55)

Gen-ID: 6624

UniProt: Q16658