Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

Fascin Antikörper

FSCN1 Reaktivität: Human, Ratte WB, IHC, FACS, IF, StM Wirt: Maus Monoclonal FSCN1-418 unconjugated
Produktnummer ABIN6940609
  • Target Alle Fascin (FSCN1) Antikörper anzeigen
    Fascin (FSCN1)
    Reaktivität
    • 90
    • 52
    • 30
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Ratte
    Wirt
    • 77
    • 35
    • 1
    • 1
    Maus
    Klonalität
    • 68
    • 46
    Monoklonal
    Konjugat
    • 47
    • 13
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Dieser Fascin Antikörper ist unkonjugiert
    Applikation
    • 80
    • 46
    • 37
    • 31
    • 28
    • 28
    • 20
    • 14
    • 11
    • 7
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF), Staining Methods (StM)
    Spezifität
    Recognizes a protein of 55 kDa, which is identified as fascin-1. Its actin binding ability is regulated by phosphorylation. Antibody to fascin-1 is a very sensitive marker for Reed-Sternberg cells and variants in nodular sclerosis, mixed cellularity, and lymphocyte depletion Hodgkin's disease. It is uniformly negative in lymphoid cells, plasma cells, and myeloid cells. Fascin-1 is also expressed in dendritic cells. This marker may be helpful to distinguish between Hodgkin lymphoma and non-Hodgkin lymphoma in difficult cases. Also, the lack of expression of fascin-1 in the neoplastic follicles in follicular lymphoma may be helpful in distinguishing these lymphomas from reactive follicular hyperplasia in which the number of follicular dendritic cells is normal or increased. Antibody to fascin-1 has been suggested as a prognostic marker in neuroendocrine neoplasms of the lung as well as in ovarian cancer. Fascin-1 expression may be induced by Epstein-Barr virus (EBV) infection of B cells with the possibility that viral induction of fascin in lymphoid or other cell types must also be considered in EBV-positive cases.
    Aufreinigung
    Purified by Protein A/G
    Immunogen
    Full length recombinant human FSCN1 protein
    Klon
    FSCN1-418
    Isotyp
    IgG2b kappa
    Top Product
    Discover our top product FSCN1 Primärantikörper
  • Applikationshinweise

    Positive Control: K562, HeLa, MCF-7, PC-3 or BEWO cells. Hodgkin's lymphoma, Ovarian or Testicular Carcinoma.

    Known Application: Western Blot (1-2 μg/mL), Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (0.5-1.0 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 1 mM EDTA, pH 8.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-80 °C
    Informationen zur Lagerung
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Haltbarkeit
    24 months
  • Target
    Fascin (FSCN1)
    Andere Bezeichnung
    FSCN1 (FSCN1 Produkte)
    Synonyme
    CG15331 antikoerper, CG1536 antikoerper, CG32858 antikoerper, Dmel\\CG32858 antikoerper, SN antikoerper, Sn antikoerper, fs(1)A1057 antikoerper, fs(1)K1421 antikoerper, fs(1)K418 antikoerper, fs(1)K473 antikoerper, fs(1)K743 antikoerper, fs(1)M45 antikoerper, p55 antikoerper, snl antikoerper, MGC75811 antikoerper, fscn1 antikoerper, sb:cb589 antikoerper, zgc:153632 antikoerper, AI663989 antikoerper, Fan1 antikoerper, fascin-1 antikoerper, Fascin antikoerper, fscn antikoerper, FAN1 antikoerper, HSN antikoerper, SNL antikoerper, fascin antikoerper, singed antikoerper, fascin actin-bundling protein 1 antikoerper, fascin actin-bundling protein 1a antikoerper, fascin actin-bundling protein 1 L homeolog antikoerper, sn antikoerper, fscn1 antikoerper, fscn1a antikoerper, Fscn1 antikoerper, fscn1.L antikoerper, FSCN1 antikoerper
    Molekulargewicht
    55kDa
    Gen-ID
    6624
    UniProt
    Q16658
Sie sind hier:
Kundenservice