FAM111A Antikörper

Produktnummer ABIN8121366

Der Kaninchen Monoklonal anti-FAM111A Antikörper wird verwendet zum Nachweis von FAM111A in Proben von Human. Er wurde validiert für IHC, WB, IF und ICC.

Kurzübersicht für FAM111A Antikörper (ABIN8121366)

Target: FAM111A (Family with Sequence Similarity 111, Member A (FAM111A))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser FAM111A Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Klon: AB2252

Produktdetails anti-FAM111A Antikörper

Verwendungszweck: FAM111A Rabbit mAb

Spezifität: This antibody detects endogenous levels of FAM111A protein.

Aufreinigung: The antibody was purified by protein A affinity chromatography.

Immunogen: Recombinant protein (or fragment).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB, 1:1000-1:5000 | IHC, 1:100-1:300 | IF, 1:100-1:300 |

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at-20°C. Avoid freeze / thaw cycles.

Details zu FAM111A

Target: FAM111A (Family with Sequence Similarity 111, Member A (FAM111A))

Andere Bezeichnung: FAM111A

Hintergrund:

Synonyms: FAM111A, KIAA1895, Serine protease FAM111A,

Background: The protein encoded by this gene is cell-cycle regulated, and has nuclear localization. The C-terminal half of the protein shares homology with trypsin-like peptidases and it contains a PCNA-interacting peptide (PIP) box, that is necessary for its co-localization with proliferating cell nuclear antigen (PCNA) . Reduced expression of this gene resulted in DNA replication defects, consistent with the demonstrated role for this gene in Simian Virus 40 (SV40) viral replication. Mutations in this gene have been associated with Kenny-Caffey syndrome (KCS) type 2 and the more severe osteocraniostenosis (OCS, also known as Gracile Bone Dysplasia) , both characterized by short stature, hypoparathyroidism, bone development abnormalities, and hypocalcemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015],

Gene Name: FAM111A, KIAA1895

Protein Name: FAM111A

Gen-ID: 63901

UniProt: Q96PZ2