FAM111A Antikörper (AA 264-314)

Produktnummer ABIN8121365

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch FAM111A in WB. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für FAM111A Antikörper (AA 264-314) (ABIN8121365)

Target: FAM111A (Family with Sequence Similarity 111, Member A (FAM111A))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FAM111A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-FAM111A Antikörper

Bindungsspezifität: AA 264-314

Verwendungszweck: F111A Antibody

Spezifität: This antibody detects endogenous levels of F111A at Human/Mouse

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human F111A AA range: 264-314

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu FAM111A

Target: FAM111A (Family with Sequence Similarity 111, Member A (FAM111A))

Andere Bezeichnung: F111A

Hintergrund:

Background: The protein encoded by this gene is cell-cycle regulated, and has nuclear localization. The C-terminal half of the protein shares homology with trypsin-like peptidases and it contains a PCNA-interacting peptide (PIP) box, that is necessary for its co-localization with proliferating cell nuclear antigen (PCNA). Reduced expression of this gene resulted in DNA replication defects, consistent with the demonstrated role for this gene in Simian Virus 40 (SV40) viral replication. Mutations in this gene have been associated with Kenny-Caffey syndrome (KCS) type 2 and the more severe osteocraniostenosis (OCS, also known as Gracile Bone Dysplasia), both characterized by short stature, hypoparathyroidism, bone development abnormalities, and hypocalcemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015],

Gene Name: FAM111A KIAA1895

Protein Name: F111A

Gen-ID: 63901

UniProt: Q96PZ2