FBXO32 Antikörper (AA 217-267)

Produktnummer ABIN8121360

Der Kaninchen Polyklonal anti-FBXO32 Antikörper wird verwendet zum Nachweis von FBXO32 in Proben von Human, Maus und Ratte. Er wurde validiert für WB.

Kurzübersicht für FBXO32 Antikörper (AA 217-267) (ABIN8121360)

Target: FBXO32 (F-Box Protein 32 (FBXO32))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FBXO32 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-FBXO32 Antikörper

Bindungsspezifität: AA 217-267

Verwendungszweck: FBX32 Antibody

Spezifität: This antibody detects endogenous levels of FBX32 at Human/Mouse/Rat

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human FBX32 AA range: 217-267

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu FBXO32

Target: FBXO32 (F-Box Protein 32 (FBXO32))

Andere Bezeichnung: FBX32

Hintergrund:

Synonyms: F-box only protein 32 (Atrogin-1) (Muscle atrophy F-box protein) (MAFbx)

Background: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs.The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2011],

Gene Name: FBXO32

Protein Name: FBX32

Gen-ID: 114907

UniProt: Q969P5