ERN1 Antikörper
Kurzübersicht für ERN1 Antikörper (ABIN8121179)
Target
Alle ERN1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- IRE1α Rabbit mAb
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Spezifität
- This antibody detects endogenous levels of IRE1α protein.
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Aufreinigung
- The antibody was purified by protein A affinity chromatography.
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Immunogen
- Recombinant protein (or fragment).
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Isotyp
- IgG
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Applikationshinweise
- WB, 1:2000-1:10000 | IHC, 1:100-1:500 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid freeze / thaw cycles
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at-20°C. Avoid freeze / thaw cycles.
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- ERN1 (Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1))
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Andere Bezeichnung
- IRE1alpha
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Hintergrund
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Synonyms: ERN1, IRE1, Serine/threonine-protein kinase/endoribonuclease IRE1, Endoplasmic reticulum-to-nucleus signaling 1, Inositol-requiring protein 1, hIRE1p, Ire1-alpha, IRE1a
Background: The protein encoded by this gene is the ER to nucleus signalling 1 protein, a human homologue of the yeast Ire1 gene product. This protein possesses intrinsic kinase activity and an endoribonuclease activity and it is important in altering gene expression as a response to endoplasmic reticulum-based stress signals. [provided by RefSeq, Jul 2008],
Gene Name: ERN1
Protein Name: IRE1α
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Gen-ID
- 2081
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UniProt
- O75460
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Pathways
- ER-Nucleus Signaling, Unfolded Protein Response
Target
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