Desmocollin 1 Antikörper (AA 749-799)

Produktnummer ABIN8120970

Der Kaninchen Polyklonal anti-Desmocollin 1 Antikörper wird verwendet zum Nachweis von Desmocollin 1 in Proben von Human und Maus. Er wurde validiert für WB.

Kurzübersicht für Desmocollin 1 Antikörper (AA 749-799) (ABIN8120970)

Target: Desmocollin 1 (DSC1)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Desmocollin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Desmocollin 1 Antikörper

Bindungsspezifität: AA 749-799

Verwendungszweck: DSC1 Antibody

Spezifität: This antibody detects endogenous levels of DSC1 at Human/Mouse

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human DSC1 AA range: 749-799

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu Desmocollin 1

Target: Desmocollin 1 (DSC1)

Andere Bezeichnung: DSC1

Hintergrund:

Background: The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. A subtype of IgA pemphigus, a life-threatening autoimmune disease, is characterized by the presence of autoantibodies that target the encoded protein. The desmosomal family members are arranged in two clusters on chromosome 18. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protein. [provided by RefSeq, Nov 2015],

Gene Name: DSC1 CDHF1

Protein Name: DSC1

Gen-ID: 1823

UniProt: Q08554