DOCK2 Antikörper

Produktnummer ABIN8120942

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch DOCK2 in IHC, ELISA und IF. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für DOCK2 Antikörper (ABIN8120942)

Target: DOCK2 (Dedicator of Cytokinesis 2 (DOCK2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DOCK2 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-DOCK2 Antikörper

Verwendungszweck: DOCK 2 Antibody

Spezifität: DOCK 2 Polyclonal Antibody detects endogenous levels of DOCK 2 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human DOCK 2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:100 - 1:300. ELISA: 1:40000. IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu DOCK2

Target: DOCK2 (Dedicator of Cytokinesis 2 (DOCK2))

Andere Bezeichnung: DOCK 2

Hintergrund:

Synonyms: DOCK2, KIAA0209, Dedicator of cytokinesis protein 2

Background: The protein encoded by this gene belongs to the CDM protein family. It is specifically expressed in hematopoietic cells and is predominantly expressed in peripheral blood leukocytes. The protein is involved in remodeling of the actin cytoskeleton required for lymphocyte migration in response to chemokine signaling. It activates members of the Rho family of GTPases, for example RAC1 and RAC2, by acting as a guanine nucleotide exchange factor (GEF) to exchange bound GDP for free GTP. [provided by RefSeq, Oct 2016],

Gene Name: DOCK2

Protein Name: Dedicator of cytokinesis protein 2

Gen-ID: 1794

UniProt: Q92608