DOCK2 Antikörper (AA 1551-1830)

Produktnummer ABIN1679578

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch DOCK2 in WB, IP und IF. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für DOCK2 Antikörper (AA 1551-1830) (ABIN1679578)

Target: DOCK2 (Dedicator of Cytokinesis 2 (DOCK2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DOCK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF)

Produktdetails anti-DOCK2 Antikörper

Bindungsspezifität: AA 1551-1830

Sequenz: FTEEYVRDHP EDQDKLTHLK DLIAWQIPFL GAGIKIHEKR VSDNLRPFHD RMEECFKNLK MKVEKEYGVR EMPDFDDRRV GRPRSMLRSY RQMSIISLAS MNSDCSTPSK PTSESFDLEL ASPKTPRVEQ EEPISPGSTL PEVKLRRSKK RTKRSSVVFA DEKAAAESDL KRLSRKHEFM SDTNLSEHAA IPLKASVLSQ MSFASQSMPT IPALALSVAG IPGLDEANTS PRLSQTFLQL SDGDKKTLTR KKVNQFFKTM LASKSAEEGK QIPDSLSTDL

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1551-1830 of human DOCK2 (NP_004937.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:1000,IF,1:50 - 1:200,IP,1:50 - 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu DOCK2

Target: DOCK2 (Dedicator of Cytokinesis 2 (DOCK2))

Andere Bezeichnung: DOCK2

Hintergrund: The protein encoded by this gene belongs to the CDM protein family. It is specifically expressed in hematopoietic cells and is predominantly expressed in peripheral blood leukocytes. The protein is involved in remodeling of the actin cytoskeleton required for lymphocyte migration in response to chemokine signaling. It activates members of the Rho family of GTPases, for example RAC1 and RAC2, by acting as a guanine nucleotide exchange factor (GEF) to exchange bound GDP for free GTP.,DOCK2,IMD40,Signal Transduction,G protein signaling,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,Stem Cells,Hematopoietic Progenitors,DOCK2

Molekulargewicht: 38 kDa/211 kDa

Gen-ID: 1794

UniProt: Q92608