CKAP5 Antikörper (AA 1446-1496)

Produktnummer ABIN8120895

Der Kaninchen Polyklonal anti-CKAP5 Antikörper wird verwendet zum Nachweis von CKAP5 in Proben von Human und Maus. Er wurde validiert für WB.

Kurzübersicht für CKAP5 Antikörper (AA 1446-1496) (ABIN8120895)

Target: CKAP5 (Cytoskeleton Associated Protein 5 (CKAP5))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CKAP5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CKAP5 Antikörper

Bindungsspezifität: AA 1446-1496

Verwendungszweck: CKAP5 Antibody

Spezifität: This antibody detects endogenous levels of CKAP5 at Human/Mouse

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human CKAP5 AA range: 1446-1496

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu CKAP5

Target: CKAP5 (Cytoskeleton Associated Protein 5 (CKAP5))

Andere Bezeichnung: CKAP5

Hintergrund:

Background: This gene encodes a cytoskeleton-associated protein which belongs to the TOG/XMAP215 family. The N-terminal half of this protein contains a microtubule-binding domain and the C-terminal half contains a KXGS motif for binding tubulin dimers. This protein has two distinct roles in spindle formation, it protects kinetochore microtubules from depolymerization and plays an essential role in centrosomal microtubule assembly. This protein may be necessary for the proper interaction of microtubules with the cell cortex for directional cell movement. It also plays a role in translation of the myelin basic protein (MBP) mRNA by interacting with heterogeneous nuclear ribonucleoprotein (hnRNP) A2, which associates with MBP. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011],

Gene Name: CKAP5 KIAA0097

Protein Name: CKAP5

Gen-ID: 9793

UniProt: Q14008

Pathways: M Phase