CYFIP1 Antikörper (AA 980-1060)

Produktnummer ABIN8120892

Der Kaninchen Polyklonal anti-CYFIP1 Antikörper wird verwendet zum Nachweis von CYFIP1 in Proben von Human, Maus und Ratte. Er wurde validiert für WB und ELISA.

Kurzübersicht für CYFIP1 Antikörper (AA 980-1060) (ABIN8120892)

Target: CYFIP1 (Cytoplasmic FMR1 Interacting Protein 1 (CYFIP1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CYFIP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-CYFIP1 Antikörper

Bindungsspezifität: AA 980-1060

Verwendungszweck: CYFP1 Antibody

Spezifität: CYFP1 Polyclonal Antibody detects endogenous levels of protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human protein . at AA range: 980-1060

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000 ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu CYFIP1

Target: CYFIP1 (Cytoplasmic FMR1 Interacting Protein 1 (CYFIP1))

Andere Bezeichnung: CYFP1

Hintergrund:

Background: function:Involved in formation of membrane ruffles and lamellipodia protrusions and in axon outgrowth. Binds to F-actin but not to RNA.,similarity:Belongs to the CYFIP family.,subcellular location:Highly expressed in the perinuclear region. Enriched in synaptosomes, membrane ruffles and at the tips of lamellipodia.,subunit:Interacts with the active GTP-bound form of RAC1. Interacts with FMR1/FMRP but does not bind to related proteins FXR1 or FXR2. Component of the WAVE2 complex composed of ABI1, CYFIP1/SRA1, NCKAP1/NAP1 and WASF2/WAVE2 (By similarity). Interacts through its C-terminus with the C-terminus of DPYSL2/CRMP2 which is necessary for DPYSL2-induced axon outgrowth.,

Gene Name: CYFIP1 KIAA0068

Protein Name: Cytoplasmic FMR1-interacting protein 1 (Specifically Rac1-associated protein 1) (Sra-1) (p140sra-1)

Gen-ID: 23191

UniProt: Q7L576