CYFIP1 Antikörper (AA 980-1060)

Produktnummer ABIN7228120

Der Kaninchen Polyklonal anti-CYFIP1 Antikörper (ABIN7228120) detektiert spezifisch CYFIP1 in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für CYFIP1 Antikörper (AA 980-1060) (ABIN7228120)

Target: CYFIP1 (Cytoplasmic FMR1 Interacting Protein 1 (CYFIP1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CYFIP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-CYFIP1 Antikörper

Bindungsspezifität: AA 980-1060

Verwendungszweck: Rabbit Anti-CYFP1 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of CYFP1 protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human CYFP1 protein at AA range: 980-1060

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu CYFIP1

Target: CYFIP1 (Cytoplasmic FMR1 Interacting Protein 1 (CYFIP1))

Andere Bezeichnung: CYFP1

Hintergrund: Cytoplasmic FMR1-interacting protein 1 ,Specifically Rac1-associated protein 1, Sra-1CYFIP1 (Cytoplasmic FMR1 Interacting Protein 1) encodes a protein that regulates cytoskeletal dynamics and protein translation. The encoded protein is a component of the WAVE regulatory complex (WRC), which promotes actin polymerization. This protein also interacts with the Fragile X mental retardation protein (FMRP) and translation initiation factor 4E to inhibit protein translation. A large chromosomal deletion including CYFIP1 is associated with increased risk of schizophrenia and epilepsy in human patients. Reduced expression of CYFIP1 has been observed in various human cancers and the encoded protein may inhibit tumor invasion. CYFIP1 is a Protein Coding gene. Diseases associated with CYFIP1 include Fragile X Syndrome and Schizophrenia. Among its related pathways are RET signaling and Regulation of actin dynamics for phagocytic cup formation.

Molekulargewicht: 137kD

Gen-ID: 23191

UniProt: Q7L576