COX1 Antikörper (AA 483-533)

Produktnummer ABIN8120860

Der Kaninchen Polyklonal anti-COX1 Antikörper (ABIN8120860) detektiert spezifisch COX1 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für COX1 Antikörper (AA 483-533) (ABIN8120860)

Target: COX1 (Cytochrome C Oxidase Subunit I (COX1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser COX1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-COX1 Antikörper

Bindungsspezifität: AA 483-533

Verwendungszweck: COX1 Antibody

Spezifität: The antibody detects endogenous COX1 proteins.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthetic Peptide of COX1 AA range: 483-533

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4, containing 0.5 % BSA, 0.02 % sodium azide as Preservative and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu COX1

Target: COX1 (Cytochrome C Oxidase Subunit I (COX1))

Andere Bezeichnung: COX1

Hintergrund:

Synonyms: PTGS1, COX1, Prostaglandin G/H synthase 1, Cyclooxygenase-1, COX-1, Prostaglandin H2 synthase 1, PGH synthase 1, PGHS-1, PHS 1, Prostaglandin-endoperoxide synthase 1

Background: This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. Based on its ability to function as both a cyclooxygenase and as a peroxidase, the encoded protein has been identified as a moonlighting protein. The protein may promote cell proliferation during tumor progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014],

Gene Name: PTGS1

Protein Name: Prostaglandin G/H synthase 1

Gen-ID: 5742

UniProt: P23219

Pathways: Proton Transport