CDKN1C Antikörper (AA 200-316)

Produktnummer ABIN8120829

Der Maus Monoklonal anti-CDKN1C Antikörper wird verwendet zum Nachweis von CDKN1C in Proben von Human. Er wurde validiert für WB, IHC, IF und ELISA.

Kurzübersicht für CDKN1C Antikörper (AA 200-316) (ABIN8120829)

Target: CDKN1C (Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CDKN1C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA

Klon: AB1575

Produktdetails anti-CDKN1C Antikörper

Bindungsspezifität: AA 200-316

Verwendungszweck: p57kip2 mouse mAb

Spezifität: This antibody detects endogenous levels of p57kip2 protein.

Aufreinigung: The antibody was purified by protein G affinity chromatography.

Immunogen: A synthetic peptide corresponding to the amino acid region 200 - 316 of the human p57kip2 protein.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC, 1:200-1:1000 | WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at-20°C. Avoid freeze / thaw cycles.

Details zu CDKN1C

Target: CDKN1C (Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C))

Andere Bezeichnung: p57kip2

Hintergrund:

Synonyms: Beckwith Wiedemann syndrome, BWCR, BWS, CDKI, CDKN 1C, CDKN1C, CDN1C_HUMAN, Cyclin dependent kinase inhibitor 1C, Cyclin dependent kinase inhibitor p57, Cyclin-dependent kinase inhibitor 1C, Cyclin-dependent kinase inhibitor p57, KIP 2, KIP2, p57, p57 Kip 2, p57KIP2, WBS

Background: This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010],

Gene Name: CDKN1C KIP2

Protein Name: p57kip2

Gen-ID: 1028

UniProt: P49918

Pathways: Zellzyklus, Dopaminergic Neurogenesis