CDK6 Antikörper

Produktnummer ABIN8120812

Der Kaninchen Monoklonal anti-CDK6 Antikörper (Klon AB1664) (ABIN8120812) detektiert spezifisch CDK6 in WB, IHC, ELISA, IF und IP. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für CDK6 Antikörper (ABIN8120812)

Target: CDK6 (Cyclin-Dependent Kinase 6 (CDK6))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser CDK6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)

Klon: AB1664

Produktdetails anti-CDK6 Antikörper

Verwendungszweck: CDK6 Rabbit mAb

Spezifität: This antibody detects endogenous levels of CDK6 protein.

Aufreinigung: The antibody was purified by protein A affinity chromatography.

Immunogen: Recombinant protein (or fragment).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB, 1:1000-1:5000 | IHC, 1:200-1:1000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at-20°C. Avoid freeze / thaw cycles.

Details zu CDK6

Target: CDK6 (Cyclin-Dependent Kinase 6 (CDK6))

Andere Bezeichnung: CDK6

Hintergrund:

Synonyms: Cyclin-dependent kinase 6 (EC 2. 7. 11. 22, Cell division protein kinase 6, Serine/threonine-protein kinase PLSTIRE)

Background: cyclin dependent kinase 6 (CDK6) Homo sapiens    The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors. This kinase, as well as CDK4, has been shown to phosphorylate, and thus regulate the activity of, tumor suppressor protein Rb. Expression of this gene is up-regulated in some types of cancer. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefS

Gene Name: CDK6 CDKN6

Protein Name: CDK6

Gen-ID: 1021

UniProt: Q00534

Pathways: Zellzyklus, Mitotic G1-G1/S Phases