CDK6 Antikörper (AA 280-325)

Produktnummer ABIN8120811

Der Kaninchen Polyklonal anti-CDK6 Antikörper wird verwendet zum Nachweis von CDK6 in Proben von Human, Maus und Ratte. Er wurde validiert für WB, IHC, ELISA und IF.

Kurzübersicht für CDK6 Antikörper (AA 280-325) (ABIN8120811)

Target: CDK6 (Cyclin-Dependent Kinase 6 (CDK6))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDK6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-CDK6 Antikörper

Bindungsspezifität: AA 280-325

Verwendungszweck: Cdk6 Antibody

Spezifität: The antibody detects endogenous Cdk6

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthetic peptide from human protein at AA range: 280-325

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000,IHC 1:500-200, ELISA 1:10000-20000. IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu CDK6

Target: CDK6 (Cyclin-Dependent Kinase 6 (CDK6))

Andere Bezeichnung: Cdk6

Hintergrund:

Synonyms: Cyclin-dependent kinase 6 (EC 2.7.11.22, Cell division protein kinase 6, Serine/threonine-protein kinase PLSTIRE)

Background: cyclin dependent kinase 6(CDK6) Homo sapiens The protein encoded byThis gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors. This kinase, as well as CDK4, has been shown to phosphorylate, and thus regulate the activity of, tumor suppressor protein Rb. Expression of this gene is up-regulated in some types of cancer. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefS

Gene Name: CDK6 CDKN6

Protein Name: Cyclin-dependent kinase 6 (EC 2.7.11.22) (Cell division protein kinase 6) (Serine/threonine-protein kinase PLSTIRE)

Gen-ID: 1021

UniProt: Q00534

Pathways: Zellzyklus, Mitotic G1-G1/S Phases