Cortactin Antikörper (acLys235)

Produktnummer ABIN8120743

Der Kaninchen Polyklonal anti-Cortactin Antikörper (ABIN8120743) detektiert spezifisch Cortactin in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für Cortactin Antikörper (acLys235) (ABIN8120743)

Target: Cortactin (CTTN)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cortactin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Cortactin Antikörper

Bindungsspezifität: acLys235

Verwendungszweck: Cortactin (Acetyl Lys235) Antibody

Spezifität: Acetyl-Cortactin (K235) Polyclonal Antibody detects endogenous levels of Cortactin protein only when acetylation at K235.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized acetyl-peptide derived from the Internal region of human Cortactin around the acetylation site of K235.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu Cortactin

Target: Cortactin (CTTN)

Andere Bezeichnung: Cortactin

Hintergrund:

Synonyms: CTTN, EMS1, Src substrate cortactin, Amplaxin, Oncogene EMS1

Background: cortactin(CTTN) Homo sapiens This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene. [provided by RefSeq, May 2010],

Gene Name: CTTN

Protein Name: Src substrate cortactin

Gen-ID: 2017

UniProt: Q14247

Pathways: MAPK Signalweg