Adipsin Antikörper (AA 101-150)

Produktnummer ABIN8120720

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Adipsin in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für Adipsin Antikörper (AA 101-150) (ABIN8120720)

Target: Adipsin (CFD) (Complement Factor D (CFD))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Adipsin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Adipsin Antikörper

Bindungsspezifität: AA 101-150

Verwendungszweck: Adipsin Antibody

Spezifität: This antibody detects endogenous levels of Human Adipsin

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human Adipsin AA range: 101-150

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-2000 ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu Adipsin

Target: Adipsin (CFD) (Complement Factor D (CFD))

Andere Bezeichnung: Adipsin

Hintergrund:

Synonyms: Complement factor D (EC 3.4.21.46, Adipsin, C3 convertase activator, Properdin factor D)

Background: catalytic activity:Selective cleavage of Arg-|-Lys bond in complement factor B when in complex with complement subcomponent C3b or with cobra venom factor.,disease:Defects in CFD are the cause of complement factor D deficiency [MIM:134350]. This deficiency predisposes to invasive meningococcal disease.,function:Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway.,online information:CFD mutation db,similarity:Belongs to the peptidase S1 family.,similarity:Contains 1 peptidase S1 domain.,

Gene Name: CFD DF PFD

Protein Name: Adipsin

Gen-ID: 1675

UniProt: P00746

Pathways: Komplementsystem