C6orf150 Antikörper

Produktnummer ABIN8120573

Dieser Kaninchen Monoklonal Antikörper detektiert spezifisch C6orf150 in WB, IHC, ELISA, IP und IF. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für C6orf150 Antikörper (ABIN8120573)

Target: C6orf150 (Chromosome 6 Open Reading Frame 150 (C6orf150))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser C6orf150 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF)

Klon: AB1873

Produktdetails anti-C6orf150 Antikörper

Verwendungszweck: cGAS Rabbit mAb

Spezifität: This antibody detects endogenous levels of cGAS protein.

Aufreinigung: The antibody was purified by protein A affinity chromatography.

Immunogen: Recombinant protein (or fragment).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB, 1:1000-1:5000 | IHC, 1:100-1:500 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at-20°C. Avoid freeze / thaw cycles.

Details zu C6orf150

Target: C6orf150 (Chromosome 6 Open Reading Frame 150 (C6orf150))

Andere Bezeichnung: cGAS

Hintergrund:

Synonyms: Protein MB21D1 (Mab-21 domain-containing protein 1)

Background: Enables several functions, including 2', 3'-cyclic GMP-AMP synthase activity, molecular condensate scaffold activity, and phosphatidylinositol-4, 5-bisphosphate binding activity. Involved in several processes, including defense response to symbiont, intracellular signal transduction, and regulation of defense response. Located in nuclear body, plasma membrane, and site of double-strand break. Is active in cytosol and nucleus. [provided by Alliance of Genome Resources, Feb 2025]

Gene Name: MB21D1 cGAS C6orf150

Protein Name: cGAS

Gen-ID: 115004

UniProt: Q8N884

Pathways: Activation of Innate immune Response