CENPF Antikörper (AA 2190-2270)

Produktnummer ABIN8120456

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch CENPF in IHC und IF. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für CENPF Antikörper (AA 2190-2270) (ABIN8120456)

Target: CENPF (Centromere Protein F (CENPF))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CENPF Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-CENPF Antikörper

Bindungsspezifität: AA 2190-2270

Verwendungszweck: CENPF Antibody

Spezifität: CENPF Polyclonal Antibody detects endogenous levels of protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human protein . at AA range: 2190-2270

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:50-300. IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu CENPF

Target: CENPF (Centromere Protein F (CENPF))

Andere Bezeichnung: CENPF

Hintergrund:

Background: This gene encodes a protein that associates with the centromere-kinetochore complex. The protein is a component of the nuclear matrix during the G2 phase of interphase. In late G2 the protein associates with the kinetochore and maintains this association through early anaphase. It localizes to the spindle midzone and the intracellular bridge in late anaphase and telophase, respectively, and is thought to be subsequently degraded. The localization of this protein suggests that it may play a role in chromosome segregation during mitotis. It is thought to form either a homodimer or heterodimer. Autoantibodies against this protein have been found in patients with cancer or graft versus host disease. [provided by RefSeq, Jul 2008],

Gene Name: CENPF

Protein Name: Centromere protein F (CENP-F) (AH antigen) (Kinetochore protein CENPF) (Mitosin)

Gen-ID: 1063

UniProt: P49454

Pathways: Chromatin Binding, M Phase, SARS-CoV-2 Protein Interaktom, Phosphorylierungen bei SARS-CoV-2 Infektion