CAMKK2 Antikörper (pSer511)
Kurzübersicht für CAMKK2 Antikörper (pSer511) (ABIN8120137)
Target
Alle CAMKK2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pSer511
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Verwendungszweck
- CaMKK2 (Phospho Ser511) Antibody
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Spezifität
- This antibody detects endogenous levels of Human Mouse Rat CaMKK2 (phospho-Ser511)
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Aufreinigung
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
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Immunogen
- Synthesized phosho peptide around human CaMKK2 (Ser511)
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Isotyp
- IgG
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Applikationshinweise
- WB 1:1000-2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C/1 year
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Haltbarkeit
- 12 months
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- CAMKK2 (Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2))
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Andere Bezeichnung
- CaMKK2
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Hintergrund
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Synonyms: Calcium/calmodulin-dependent protein kinase kinase 2 (CaM-KK 2) (CaM-kinase kinase 2) (CaMKK 2) (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase beta) (CaM-KK beta) (CaM-kinase kinase beta) (CaMKK beta)
Background: The product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. The major isoform of this gene plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. Protein products of this gene also phosphorylate AMP-activated protein kinase (AMPK). This gene has its strongest expression in the brain and influences signalling cascades involved with learning and memory, neuronal differentiation and migration, neurite outgrowth, and synapse formation. Alternative splicing results in multiple transcript variants encoding distinct isoforms. The identified isoforms differ in their ability to undergo autophosphorylation and to phosphorylate downstream kinases. [provided by RefSeq, Jul 2012],
Gene Name: CAMKK2 CAMKKB KIAA0787
Protein Name: CaMKK2 (Ser511)
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Gen-ID
- 10645
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UniProt
- Q96RR4
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Pathways
- AMPK Signaling
Target
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