CAMLG Antikörper
Kurzübersicht für CAMLG Antikörper (ABIN8120132)
Target
Alle CAMLG Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Verwendungszweck
- CAMLG Antibody
-
Spezifität
- CAMLG Polyclonal Antibody detects endogenous levels of protein.
-
Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
Immunogen
- Synthesized peptide derived from part region of human protein
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- WB 1:500-2000 ELISA 1:5000-20000
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store at -20°C/1 year
-
Haltbarkeit
- 12 months
-
-
- CAMLG (Calcium Modulating Ligand (CAMLG))
-
Andere Bezeichnung
- CAMLG
-
Hintergrund
-
Background: The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin.The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin. [provided by RefSeq, Jul 2008],
Gene Name: CAMLG CAML
Protein Name: Calcium signal-modulating cyclophilin ligand (CAML)
-
Gen-ID
- 819
-
UniProt
- P49069
-
Pathways
- EGFR Signaling Pathway
Target
-