POT1 Antikörper (C-Term)

Produktnummer ABIN8109220

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch POT1 in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für POT1 Antikörper (C-Term) (ABIN8109220)

Target: POT1 (Protection of Telomeres 1 (POT1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser POT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-POT1 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: POT1 Antibody - C-terminal region

Sequenz: QNTSLYDSKI WTTKNQKGRK VAVHFVKNNG ILPLSNECLL LIEGGTLSEI

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human POTE1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP74137-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu POT1

Target: POT1 (Protection of Telomeres 1 (POT1))

Andere Bezeichnung: POT1

Hintergrund:

Background Information: This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described.

Gene Name: protection of telomeres 1

Alternative Symbols: GLM9, CMM10, HPOT1

Protein Name: protection of telomeres protein 1

Molekulargewicht: 69kDa

Gen-ID: 25913

NCBI Accession: XP_006715980

UniProt: Q9NUX5

Pathways: Zellzyklus, Telomere Maintenance